EPZ031686

Modify Date: 2024-01-06 15:35:13

EPZ031686 Structure
EPZ031686 structure
Common Name EPZ031686
CAS Number 1808011-22-4 Molecular Weight 591.086
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C26H34ClF3N4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EPZ031686


EPZ031686 is an orally available SMYD3 inhibitor with an IC50 of 3 nM in cell-free assay.

 Names

Name EPZ031686
Synonym More Synonyms

 EPZ031686 Biological Activity

Description EPZ031686 is an orally available SMYD3 inhibitor with an IC50 of 3 nM in cell-free assay.
Related Catalog
References

[1]. Mitchell LH et al. Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor. ACS Med Chem Lett. 2015 Aug 27;7(2):134-8.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C26H34ClF3N4O4S
Molecular Weight 591.086
Exact Mass 590.194153
LogP 3.44
Index of Refraction 1.603
Storage condition 2-8℃

 Synonyms

6-Chloro-2-oxo-N-[(3-endo)-8-({[1-(4,4,4-trifluorobutyl)-4-piperidinyl]methyl}sulfonyl)-8-azabicyclo[3.2.1]oct-3-yl]-5-indolinecarboxamide
MFCD30181978
1H-Indole-5-carboxamide, 6-chloro-2,3-dihydro-2-oxo-N-[(3-endo)-8-[[[1-(4,4,4-trifluorobutyl)-4-piperidinyl]methyl]sulfonyl]-8-azabicyclo[3.2.1]oct-3-yl]-
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Price: $546/10mM*1mLinDMSO

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