2-(t-Butoxycarbonylamido)-1,3-bis(PFP-oxycarbonylethoxy)propane

Modify Date: 2024-01-05 12:14:24

2-(t-Butoxycarbonylamido)-1,3-bis(PFP-oxycarbonylethoxy)propane Structure
2-(t-Butoxycarbonylamido)-1,3-bis(PFP-oxycarbonylethoxy)propane structure
Common Name 2-(t-Butoxycarbonylamido)-1,3-bis(PFP-oxycarbonylethoxy)propane
CAS Number 1807521-01-2 Molecular Weight 667.45
Density N/A Boiling Point N/A
Molecular Formula C26H23F10NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-(t-Butoxycarbonylamido)-1,3-bis(PFP-oxycarbonylethoxy)propane


C-NH-Boc-C-Bis-(C1-PEG1-PFP) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name C-NH-Boc-C-Bis-(C1-PEG1-PFP)
Synonym More Synonyms

  Biological Activity

Description C-NH-Boc-C-Bis-(C1-PEG1-PFP) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C26H23F10NO8
Molecular Weight 667.45

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD28385477
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