N-(5-Hydroxypentyl)maleimide

Modify Date: 2024-01-15 17:40:51

N-(5-Hydroxypentyl)maleimide structure	Common Name	N-(5-Hydroxypentyl)maleimide
	CAS Number	180608-78-0	Molecular Weight	183.20
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₁₃NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N-(5-Hydroxypentyl)maleimide

N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) )[1].

Name	N-(5-Hydroxypentyl)maleimide

Description	N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) )[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker)[1].
References	[1]. Finniss, M. C., et al. A versatile acid-labile linker for antibody–drug conjugates. Med. Chem. Commun., 2014, 5(9), 1355-1358.

Molecular Formula	C₉H₁₃NO₃
Molecular Weight	183.20
Storage condition	2-8°C