3’-β-C-Ethynylguanosine

Modify Date: 2024-04-06 11:38:02

3’-β-C-Ethynylguanosine Structure
3’-β-C-Ethynylguanosine structure
Common Name 3’-β-C-Ethynylguanosine
CAS Number 180300-56-5 Molecular Weight 307.26
Density N/A Boiling Point N/A
Molecular Formula C12H13N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3’-β-C-Ethynylguanosine


3’-β-C-Ethynylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

 Names

Name 3’-β-C-Ethynylguanosine

 3’-β-C-Ethynylguanosine Biological Activity

Description 3’-β-C-Ethynylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

 Chemical & Physical Properties

Molecular Formula C12H13N5O5
Molecular Weight 307.26
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