Methyltetrazine-PEG4-amine HCl

Modify Date: 2025-08-25 11:15:34

Methyltetrazine-PEG4-amine HCl Structure
Methyltetrazine-PEG4-amine HCl structure
Common Name Methyltetrazine-PEG4-amine HCl
CAS Number 1802908-05-9 Molecular Weight 363.411
Density 1.2±0.1 g/cm3 Boiling Point 558.7±60.0 °C at 760 mmHg
Molecular Formula C17H25N5O4 Melting Point N/A
MSDS N/A Flash Point 291.7±32.9 °C

 Use of Methyltetrazine-PEG4-amine HCl


Methyltetrazine-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Methyltetrazine-PEG4-Amine
Synonym More Synonyms

 Methyltetrazine-PEG4-amine HCl Biological Activity

Description Methyltetrazine-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 558.7±60.0 °C at 760 mmHg
Molecular Formula C17H25N5O4
Molecular Weight 363.411
Flash Point 291.7±32.9 °C
Exact Mass 363.190643
LogP -0.73
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.539
InChIKey JOEAATMYJGXMGS-UHFFFAOYSA-N
SMILES Cc1nnc(-c2ccc(OCCOCCOCCOCCN)cc2)nn1

 Synonyms

2-[2-(2-{2-[4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy}ethoxy)ethoxy]ethanamine
Ethanamine, 2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]-
MFCD28334553
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