1-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy)-3,6,9,12-tetraoxapentadecan-15-oic acid

Modify Date: 2025-08-24 20:10:05

1-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy)-3,6,9,12-tetraoxapentadecan-15-oic acid structure	Common Name	1-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy)-3,6,9,12-tetraoxapentadecan-15-oic acid
	CAS Number	1802907-91-0	Molecular Weight	436.459
	Density	1.2±0.1 g/cm3	Boiling Point	647.6±65.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₈N₄O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	345.5±34.3 °C

Use of 1-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy)-3,6,9,12-tetraoxapentadecan-15-oic acid

Methyltetrazine-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Methyltetrazine-PEG4-Acid
Synonym	More Synonyms

Description	Methyltetrazine-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.2±0.1 g/cm3
Boiling Point	647.6±65.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₈N₄O₇
Molecular Weight	436.459
Flash Point	345.5±34.3 °C
Exact Mass	436.195801
LogP	-0.70
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.533
InChIKey	LMFGOJBYDNENPR-UHFFFAOYSA-N
SMILES	Cc1nnc(-c2ccc(OCCOCCOCCOCCOCCC(=O)O)cc2)nn1

3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-

MFCD28334558

1-[4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12-tetraoxapentadecan-15-oic acid