Methyltetrazine-PEG5-NHS ester

Modify Date: 2024-01-10 15:10:58

Methyltetrazine-PEG5-NHS ester Structure
Methyltetrazine-PEG5-NHS ester structure
Common Name Methyltetrazine-PEG5-NHS ester
CAS Number 1802907-92-1 Molecular Weight 533.53
Density N/A Boiling Point N/A
Molecular Formula C24H31N5O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methyltetrazine-PEG5-NHS ester


Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Methyltetrazine-PEG5-NHS ester

 Methyltetrazine-PEG5-NHS ester Biological Activity

Description Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H31N5O9
Molecular Weight 533.53
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