PSB-12553

Modify Date: 2025-08-27 05:51:19

PSB-12553 Structure
PSB-12553 structure
Common Name PSB-12553
CAS Number 1802226-88-5 Molecular Weight 532.401
Density N/A Boiling Point N/A
Molecular Formula C18H22N4O9P2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PSB-12553


PSB-12553 is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 9.5 nM for rat recombinant eN; displays high selectivity versus other ecto-nucleotidases and ADP-activated P2Y receptors, has high metabolic stability.

 Names

Name PSB-12553

 PSB-12553 Biological Activity

Description PSB-12553 is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 9.5 nM for rat recombinant eN; displays high selectivity versus other ecto-nucleotidases and ADP-activated P2Y receptors, has high metabolic stability.
References References 1. Bhattarai S, et al. J Med Chem. 2015 Aug 13;58(15):6248-63. View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C18H22N4O9P2S
Molecular Weight 532.401
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