CA-4948
Modify Date: 2025-09-09 11:56:32
CA-4948 structure
|
Common Name | CA-4948 | ||
|---|---|---|---|---|
| CAS Number | 1801343-74-7 | Molecular Weight | 417.42 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H19N7O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CA-4948CA-4948 is a selective and potent IRAK4 inhibitor. |
| Name | CA-4948 |
|---|---|
| Synonym | More Synonyms |
| Description | CA-4948 is a selective and potent IRAK4 inhibitor. |
|---|---|
| Related Catalog | |
| Target |
IRAK4[1] |
| In Vivo | CA-4948 is a selective and potent IRAK4 inhibitor which can be used as a therapeutic agent for hematological cancers with dysregulated TLR/MYD88/IRAK4 signaling. CA-4948 exhibits favorable DMPK properties, oral bioavailability, and is well tolerated in mice. Furthermore, CA-4948 is previously shown to exhibit dose-dependent efficacy in ABC-DLBCL MYD88-L265P xenograft tumor models[1]. |
| References |
| Molecular Formula | C21H19N7O3 |
|---|---|
| Molecular Weight | 417.42 |
| Storage condition | -20℃ |
| N-(1-(6'-amino-[2,3'-bipyridin]-5-yl)vinyl)-2-morpholinooxazolo[4,5-c]pyridin-6-amine |