LFS-1107

Modify Date: 2024-01-02 12:17:03

LFS-1107 structure	Common Name	LFS-1107
	CAS Number	1799330-91-8	Molecular Weight	305.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₁N₅OS₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LFS-1107

LFS-1107 is a reversible CRM1 inhibitor (Kd: 12.5 pM). LFS-1107 can selectively eliminate extranodal natural killer/T cell lymphoma (ENKTL) cells and can be used for cancer research[1].

Name	LFS-1107

Description	LFS-1107 is a reversible CRM1 inhibitor (Kd: 12.5 pM). LFS-1107 can selectively eliminate extranodal natural killer/T cell lymphoma (ENKTL) cells and can be used for cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Survivin Signaling Pathways >> Membrane Transporter/Ion Channel >> CRM1 Signaling Pathways >> Apoptosis >> c-Myc Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-2
References	[1]. He Liu, et al. Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma eLife 12:e80625.

Molecular Formula	C₁₂H₁₁N₅OS₂
Molecular Weight	305.38

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LFS-1107

Use of LFS-1107

Names

LFS-1107 Biological Activity

Chemical & Physical Properties