LY3104607

Modify Date: 2025-08-25 19:29:03

LY3104607 Structure
LY3104607 structure
Common Name LY3104607
CAS Number 1795232-22-2 Molecular Weight 439.515
Density N/A Boiling Point N/A
Molecular Formula C27H25N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LY3104607


LY3104607 (LY-3104607) is a potent, selective, orally available GPR40 agonist with Ki of 15 nM, β-arrestin EC50 of 108 nM; demonstrates functional potency and glucose dependent insulin secretion in primary islets from rats; dose-dependently reduces glucose levels in vivo.

 Names

Name LY3104607

 LY3104607 Biological Activity

Description LY3104607 (LY-3104607) is a potent, selective, orally available GPR40 agonist with Ki of 15 nM, β-arrestin EC50 of 108 nM; demonstrates functional potency and glucose dependent insulin secretion in primary islets from rats; dose-dependently reduces glucose levels in vivo.
References References 1. Hamdouchi C, et al. J Med Chem. 2017 Dec 13. doi: 10.1021/acs.jmedchem.7b01411. View Related Products by Target Free Fatty Acid Receptor (FFAR)

 Chemical & Physical Properties

Molecular Formula C27H25N3O3
Molecular Weight 439.515
InChIKey FDIWCHYTKOPHPS-QFIPXVFZSA-N
SMILES CC#CC(CC(=O)O)c1ccc(OCc2ccc3nc(-c4c(C)cccc4C)nn3c2)cc1
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