LY3104607

Names

[ Name ]:
LY3104607

Biological Activity

[Description]:

LY3104607 (LY-3104607) is a potent, selective, orally available GPR40 agonist with Ki of 15 nM, β-arrestin EC50 of 108 nM; demonstrates functional potency and glucose dependent insulin secretion in primary islets from rats; dose-dependently reduces glucose levels in vivo.

[References]

References 1. Hamdouchi C, et al. J Med Chem. 2017 Dec 13. doi: 10.1021/acs.jmedchem.7b01411. View Related Products by Target Free Fatty Acid Receptor (FFAR)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₅N₃O₃

[ Molecular Weight ]:
439.515

Related Compounds

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