3’-O-Me-C(Bz)-2’-phosphoramidite

Modify Date: 2024-01-20 07:32:16

3’-O-Me-C(Bz)-2’-phosphoramidite Structure
3’-O-Me-C(Bz)-2’-phosphoramidite structure
Common Name 3’-O-Me-C(Bz)-2’-phosphoramidite
CAS Number 179479-03-9 Molecular Weight 882.92
Density N/A Boiling Point N/A
Molecular Formula C47H56N4O9P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3’-O-Me-C(Bz)-2’-phosphoramidite


3’-O-Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 3’-O-Me-C(Bz)-2’-phosphoramidite

 3’-O-Me-C(Bz)-2’-phosphoramidite Biological Activity

Description 3’-O-Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C47H56N4O9P2
Molecular Weight 882.92
InChIKey BENGZEFYMXNUAR-UHFFFAOYSA-N
SMILES COc1ccc(C(OCC2OC(n3ccc(NC(=O)c4ccccc4)nc3=O)C(OP(OCCC#N)N(C(C)C)C(C)C)C2OC)(c2ccccc2)c2ccc(OC)cc2)cc1
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