Pirimiphos-methyl-d6

Modify Date: 2024-01-02 12:18:00

Pirimiphos-methyl-d6 Structure
Pirimiphos-methyl-d6 structure
Common Name Pirimiphos-methyl-d6
CAS Number 1793055-06-7 Molecular Weight 311.371
Density 1.2±0.1 g/cm3 Boiling Point 386.5±52.0 °C at 760 mmHg
Molecular Formula C11H14D6N3O3PS Melting Point N/A
MSDS N/A Flash Point 187.6±30.7 °C

 Use of Pirimiphos-methyl-d6


Pirimiphos-methyl-d6 is the deuterium labeled Pirimiphos-methyl. Pirimiphos-methyl is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains[1][2][3].

 Names

Name O-[2-(Diethylamino)-6-methyl-4-pyrimidinyl] O,O-bis[(2H3)methyl] phosphorothioate
Synonym More Synonyms

 Pirimiphos-methyl-d6 Biological Activity

Description Pirimiphos-methyl-d6 is the deuterium labeled Pirimiphos-methyl. Pirimiphos-methyl is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains[1][2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Shizhuang Weng, et al. Detection of Pirimiphos-Methyl in Wheat Using Surface-Enhanced Raman Spectroscopy and Chemometric Methods. Molecules. 2019 Apr 30;24(9):1691.

[3]. Pål A Olsvik, et al. In Vitro Toxicity of Pirimiphos-Methyl in Atlantic Salmon Hepatocytes. Toxicol In Vitro. 2017 Mar;39:1-14.

[4]. Esther Borrás, et al. Atmospheric Degradation of the Organothiophosphate Insecticide - Pirimiphos-methyl. Sci Total Environ. 2017 Feb 1;579:1-9.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 386.5±52.0 °C at 760 mmHg
Molecular Formula C11H14D6N3O3PS
Molecular Weight 311.371
Flash Point 187.6±30.7 °C
Exact Mass 311.133972
LogP 4.00
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.555

 Synonyms

Phosphorothioic acid, O-[2-(diethylamino)-6-methyl-4-pyrimidinyl] O,O-dimethyl-d3 ester
O-[2-(Diethylamino)-6-methyl-4-pyrimidinyl] O,O-bis[(2H3)methyl] phosphorothioate