(R)-Gyramide A hydrochloride
Modify Date: 2025-09-09 19:46:22
(R)-Gyramide A hydrochloride structure
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Common Name | (R)-Gyramide A hydrochloride | ||
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| CAS Number | 1793050-70-0 | Molecular Weight | 442.975 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H28ClFN2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (R)-Gyramide A hydrochloride(R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 µM. (R)-Gyramide A hydrochloride demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs of 10-80 µM). (R)-Gyramide A hydrochloride does not affect the closely related enzyme topoisomerase IV. |
| Name | 5-Fluoro-N-[(3R)-1-(4-isopropoxybenzyl)-3-pyrrolidinyl]-2-methylbenzenesulfonamide hydrochloride (1:1) |
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| Synonym | More Synonyms |
| Description | (R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 µM. (R)-Gyramide A hydrochloride demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs of 10-80 µM). (R)-Gyramide A hydrochloride does not affect the closely related enzyme topoisomerase IV. |
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| Molecular Formula | C21H28ClFN2O3S |
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| Molecular Weight | 442.975 |
| Exact Mass | 442.149323 |
| 5-Fluoro-N-[(3R)-1-(4-isopropoxybenzyl)-3-pyrrolidinyl]-2-methylbenzenesulfonamide hydrochloride (1:1) |
| Benzenesulfonamide, 5-fluoro-2-methyl-N-[(3R)-1-[[4-(1-methylethoxy)phenyl]methyl]-3-pyrrolidinyl]-, hydrochloride (1:1) |