Calciseptin

Modify Date: 2025-08-27 00:14:21

Calciseptin Structure
Calciseptin structure
 Common Name Calciseptin
CAS Number 178805-91-9 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Calciseptin


Calciseptine, a natural?neurotoxin?isolated from the black mamba Dendroaspis p. polylepis venom. Calciseptine consists of 60 amino acids with four disulfide bonds. Calciseptine specifically blocks L-type?calcium channel[1].

 Names

Name CALCISEPTINE

 Calciseptin Biological Activity

Description Calciseptine, a natural?neurotoxin?isolated from the black mamba Dendroaspis p. polylepis venom. Calciseptine consists of 60 amino acids with four disulfide bonds. Calciseptine specifically blocks L-type?calcium channel[1].
Related Catalog
Target

L-type calcium channel:15 nM (IC50)

References

[1]. H Schweitz, et al. Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons. Proc Natl Acad Sci U S A. 1994 Feb 1; 91(3): 878–882.  

 Chemical & Physical Properties

Storage condition ?20°C
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