C 021 dihydrochloride
Modify Date: 2025-08-22 20:36:35
C 021 dihydrochloride structure
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Common Name | C 021 dihydrochloride | ||
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| CAS Number | 1784252-84-1 | Molecular Weight | 540.569 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H41N5O2.2HCl | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of C 021 dihydrochlorideC-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively. |
| Name | 2-(1,4'-Bipiperidin-1'-yl)-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride |
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| Synonym | More Synonyms |
| Description | C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively. |
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| References | References 1. Yokoyama K, et al. Bioorg Med Chem. 2009 Jan 1;17(1):64-73. View Related Products by Target Chemokine Receptor (CCR and CXCR) |
| Molecular Formula | C27H41N5O2.2HCl |
|---|---|
| Molecular Weight | 540.569 |
| Exact Mass | 539.279358 |
| InChIKey | GKJKNYQUFAPLOQ-UHFFFAOYSA-N |
| SMILES | COc1cc2nc(N3CCC(N4CCCCC4)CC3)nc(NC3CCCCCC3)c2cc1OC.Cl.Cl |
| Storage condition | 2-8°C |
| MFCD16618393 |
| 2-(1,4'-Bipiperidin-1'-yl)-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine dihydrochloride |
| 2-(1,4'-Bipiperidin-1'-yl)-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride |
| 4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-, hydrochloride (1:2) |