C 021 dihydrochloride

Modify Date: 2024-04-05 01:21:16

C 021 dihydrochloride Structure
C 021 dihydrochloride structure
Common Name C 021 dihydrochloride
CAS Number 1784252-84-1 Molecular Weight 540.569
Density N/A Boiling Point N/A
Molecular Formula C27H41N5O2.2HCl Melting Point N/A
MSDS N/A Flash Point N/A

 Use of C 021 dihydrochloride


C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively.

 Names

Name 2-(1,4'-Bipiperidin-1'-yl)-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride
Synonym More Synonyms

 C 021 dihydrochloride Biological Activity

Description C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively.
References References 1. Yokoyama K, et al. Bioorg Med Chem. 2009 Jan 1;17(1):64-73. View Related Products by Target Chemokine Receptor (CCR and CXCR)

 Chemical & Physical Properties

Molecular Formula C27H41N5O2.2HCl
Molecular Weight 540.569
Exact Mass 539.279358
Storage condition 2-8°C

 Synonyms

MFCD16618393
2-(1,4'-Bipiperidin-1'-yl)-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine dihydrochloride
2-(1,4'-Bipiperidin-1'-yl)-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride
4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-, hydrochloride (1:2)