CBR-096-4
Modify Date: 2024-04-11 11:11:19
CBR-096-4 structure
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Common Name | CBR-096-4 | ||
|---|---|---|---|---|
| CAS Number | 1776931-05-5 | Molecular Weight | 636.757 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H40N8O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CBR-096-4A derivative of the antifungal drug itraconazole (ITA) as an inhibitor of MFB cell fate in resident fibroblasts derived from multiple murine and human tissues; devoid of antifungal and human cytochrome P450 inhibitory activity with excellent pharmacokinetics, safety, and efficacy in rodent models of lung, liver, and skin fibrosis. |
| Name | CBR-096-4 |
|---|
| Description | A derivative of the antifungal drug itraconazole (ITA) as an inhibitor of MFB cell fate in resident fibroblasts derived from multiple murine and human tissues; devoid of antifungal and human cytochrome P450 inhibitory activity with excellent pharmacokinetics, safety, and efficacy in rodent models of lung, liver, and skin fibrosis. |
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| References | References 1. Bollong MJ, et al. Proc Natl Acad Sci U S A. 2017 May 2;114(18):4679-4684. View Related Products by Target Other Targets |
| Molecular Formula | C35H40N8O4 |
|---|---|
| Molecular Weight | 636.757 |