CBR-096-4

Names

[ Name ]:
CBR-096-4

Biological Activity

[Description]:

A derivative of the antifungal drug itraconazole (ITA) as an inhibitor of MFB cell fate in resident fibroblasts derived from multiple murine and human tissues; devoid of antifungal and human cytochrome P450 inhibitory activity with excellent pharmacokinetics, safety, and efficacy in rodent models of lung, liver, and skin fibrosis.

[References]

References 1. Bollong MJ, et al. Proc Natl Acad Sci U S A. 2017 May 2;114(18):4679-4684. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₅H₄₀N₈O₄

[ Molecular Weight ]:
636.757

Related Compounds

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