Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride

Modify Date: 2024-01-10 18:38:24

Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride Structure
Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride structure
 Common Name Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride
CAS Number 174422-72-1 Molecular Weight 287.74
Density N/A Boiling Point N/A
Molecular Formula C12H18ClN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride


Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 4-[N-MALEIMIDOMETHYL]CYCLOHEXANE-1-CARBOXYLHYDRAZIDE HCL 1/2 DIOXANE

  Biological Activity

Description Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H18ClN3O3
Molecular Weight 287.74
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Chemsrc provides CAS#:174422-72-1 MSDS, density, melting point, boiling point, structure, etc. Its name is Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride>> amp version: Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride

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