Norbiotinamine
Modify Date: 2025-08-26 19:12:19
Norbiotinamine structure
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Common Name | Norbiotinamine | ||
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| CAS Number | 173401-47-3 | Molecular Weight | 215.32 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H17N3OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NorbiotinamineNorbiotinamine is an alternative to biotin. Norbiotinamine can be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction[1]. |
| Name | Norbiotinamine |
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| Description | Norbiotinamine is an alternative to biotin. Norbiotinamine can be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction[1]. |
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| Related Catalog | |
| In Vitro | In order to couple biotin to amino acids, reaction has to be with an amino group. An example is biocytin (biotin lysine). However, Norbiotinamine could be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction. As an example, Norbiotinamine is coupled with the NHS ester of N-Boc-glutamic acid γ-benzyl ester. The resulting norbiotinylamide of γglutamic acid (VII), obtained after deprotection, is similar to biocytin, but it has a shorter aliphatic chain and an inverted amide bond[1]. |
| References |
[1]. Szalecki W.Synthesis of Norbiotinamine and its derivatives. Bioconjug Chem. 1996 Mar-Apr;7(2):271-3. |
| Molecular Formula | C9H17N3OS |
|---|---|
| Molecular Weight | 215.32 |
| InChIKey | KRWAZHNVQMITHZ-FXQIFTODSA-N |
| SMILES | NCCCCC1SCC2NC(=O)NC21 |