Oleanolic acid derivative 1

Modify Date: 2024-01-02 18:53:09

Oleanolic acid derivative 1 Structure
Oleanolic acid derivative 1 structure
Common Name Oleanolic acid derivative 1
CAS Number 1724-18-1 Molecular Weight 452.712
Density 1.0±0.1 g/cm3 Boiling Point 503.3±50.0 °C at 760 mmHg
Molecular Formula C31H48O2 Melting Point N/A
MSDS N/A Flash Point 255.1±17.7 °C

 Use of Oleanolic acid derivative 1


Oleanolic acid derivative 1 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.

 Names

Name Oleanolic acid derivative 1
Synonym More Synonyms

 Oleanolic acid derivative 1 Biological Activity

Description Oleanolic acid derivative 1 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.
Related Catalog
In Vitro Oleanolic acid suppress transcription or translation of inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) genes. HY-18002 is extracted from the reference, compound 9a. In the strategy, it was ambiguous whether phosphorus pentachloride (PCl5) would give the desired ring contraction product 9a (HY-18002) in the first step according to classical procedures[1].
References

[1]. Tadashi Honda, et al. Design and Synthesis of 23,24-Dinoroleanolic Acid Derivatives, Novel Triterpenoid-Steroid Hybrid Molecules. J. Org. Chem., 1998, 63 (14), pp 4846-4849.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 503.3±50.0 °C at 760 mmHg
Molecular Formula C31H48O2
Molecular Weight 452.712
Flash Point 255.1±17.7 °C
Exact Mass 452.365417
LogP 11.13
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.540
Storage condition 2-8℃

 Synonyms

Methyl (3aR,5aR,5bS,7aS,11aS,13aR,13bS)-3-isopropylidene-5a,5b,10,10,13b-pentamethyl-1,2,3,3a,4,5,5a,5b,6,7,8,9,10,11,11a,13,13a,13b-octadecahydro-7aH-cyclopenta[a]chrysene-7a-carboxylate
7aH-Cyclopenta[a]chrysene-7a-carboxylic acid, 1,2,3,3a,4,5,5a,5b,6,7,8,9,10,11,11a,13,13a,13b-octadecahydro-5a,5b,10,10,13b-pentamethyl-3-(1-methylethylidene)-, methyl ester, (3aR,5aR,5bS,7aS,11aS,13aR,13bS)-