211516-63-1

211516-63-1 structure
211516-63-1 structure
  • Name: Oleanolic acid derivative 2
  • Chemical Name: Oleanolic acid derivative 2
  • CAS Number: 211516-63-1
  • Molecular Formula: C28H42O3
  • Molecular Weight: 426.631
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2018-02-26 01:39:43
  • Modify Date: 2024-01-19 14:07:05
  • Oleanolic acid derivative 2 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.

Name Oleanolic acid derivative 2
Synonyms 7aH-Cyclopenta[a]chrysene-7a-carboxylic acid, 1,2,3,3a,4,5,5a,5b,6,7,8,9,10,11,11a,13,13a,13b-octadecahydro-5a,5b,10,10,13b-pentamethyl-3-oxo-, methyl ester, (3aR,5aR,5bS,7aS,11aS,13aR,13bR)-
Methyl (3aR,5aR,5bS,7aS,11aS,13aR,13bR)-5a,5b,10,10,13b-pentamethyl-3-oxo-1,2,3,3a,4,5,5a,5b,6,7,8,9,10,11,11a,13,13a,13b-octadecahydro-7aH-cyclopenta[a]chrysene-7a-carboxylate
Description Oleanolic acid derivative 2 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.
Related Catalog
In Vitro Oleanolic acid suppress transcription or translation of inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) genes. HY-18003 is extracted from the reference, compound 12a. For the transformation of olefin 9a (HY-18002) into ketone 12a (HY-18003), the obvious ozonolysis cannot be used because ozone also reacts with the C-12 olefin of oleanane triterpenoids to give the 12R,13R-epoxide, 12-ketone,9 and 12R-hydroxy lactone.[1].
References

[1]. Tadashi Honda, et al. Design and Synthesis of 23,24-Dinoroleanolic Acid Derivatives, Novel Triterpenoid-Steroid Hybrid Molecules. J. Org. Chem., 1998, 63 (14), pp 4846-4849.

Density 1.1±0.1 g/cm3
Boiling Point 498.6±45.0 °C at 760 mmHg
Molecular Formula C28H42O3
Molecular Weight 426.631
Flash Point 210.2±28.8 °C
Exact Mass 426.313385
LogP 7.38
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.544
Storage condition 2-8℃