TAPI-1

Modify Date: 2024-01-02 17:36:36

TAPI-1 Structure
TAPI-1 structure
Common Name TAPI-1
CAS Number 171235-71-5 Molecular Weight 499.603
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C26H37N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TAPI-1


(S,S)-TAPI-1 is an isomer of TAPI-1. TAPI-1 is a TACE (ADAM17) inhibitor and blocks the shedding of several cell surface proteins. TAPI-1 is also a metalloproteinase (MMP) inhibitor[1][2].

 Names

Name L-​Alaninamide, N-​[2-​[2-​(hydroxyamino)​-​2-​oxoethyl]​-​4-​methyl-​1-​oxopentyl]​-​3-​(2-​naphthalenyl)​-​L-​alanyl-​N-​(2-​aminoethyl)​- (9CI)
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Molecular Formula C26H37N5O5
Molecular Weight 499.603
Exact Mass 499.279480
PSA 162.65000
LogP 1.29
Index of Refraction 1.581
Storage condition -20℃

 Synonyms

L-Alaninamide, N-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-
N-{2-[2-(Hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-(2-naphthyl)-L-alanyl-N-(2-aminoethyl)-L-alaninamide
TAPI-1