TAPI-1
Modify Date: 2025-08-25 18:32:07
TAPI-1 structure
|
Common Name | TAPI-1 | ||
|---|---|---|---|---|
| CAS Number | 171235-71-5 | Molecular Weight | 499.603 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C26H37N5O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TAPI-1(S,S)-TAPI-1 is an isomer of TAPI-1. TAPI-1 is a TACE (ADAM17) inhibitor and blocks the shedding of several cell surface proteins. TAPI-1 is also a metalloproteinase (MMP) inhibitor[1][2]. |
| Name | L-Alaninamide, N-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)- (9CI) |
|---|---|
| Synonym | More Synonyms |
| Description | (S,S)-TAPI-1 is an isomer of TAPI-1. TAPI-1 is a TACE (ADAM17) inhibitor and blocks the shedding of several cell surface proteins. TAPI-1 is also a metalloproteinase (MMP) inhibitor[1][2]. |
|---|---|
| Related Catalog | |
| Target |
TACE (ADAM17), MMP[1][2] |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C26H37N5O5 |
| Molecular Weight | 499.603 |
| Exact Mass | 499.279480 |
| PSA | 162.65000 |
| LogP | 1.29 |
| Index of Refraction | 1.581 |
| InChIKey | AWNBSWDIOCXWJW-JHJOLFGTSA-N |
| SMILES | CC(C)CC(CC(=O)NO)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)NC(C)C(=O)NCCN |
| Storage condition | -20℃ |
| L-Alaninamide, N-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)- |
| N-{2-[2-(Hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-(2-naphthyl)-L-alanyl-N-(2-aminoethyl)-L-alaninamide |
| TAPI-1 |