Sapienic acid
Modify Date: 2024-01-03 09:38:01
Sapienic acid structure
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Common Name | Sapienic acid | ||
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| CAS Number | 17004-51-2 | Molecular Weight | 254.40800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H30O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Sapienic acidSapienic acid is a fatty acid commonly found on the skin and in mucosa. Sapienic acid has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively[1]. |
| Name | sapienic acid |
|---|
| Description | Sapienic acid is a fatty acid commonly found on the skin and in mucosa. Sapienic acid has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively[1]. |
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| Related Catalog | |
| Target |
MBC: 31.3 μg/mL (Streptococcus sanguinis), 375.0 μg/mL (Streptococcus mitis) and 93.8 μg/mL (Fusobacterium nucleatum)[1] |
| In Vitro | Sapienic acid (minimum bactericidal concentrations (MBCs) range, 31.3 to 375.0 μg/mL) is active against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum but not active against Escherichia coli, Staphylococcus aureus, S. marcescens, P. aeruginosa, Corynebacterium bovis, Corynebacterium striatum, and Corynebacterium jeikeium (MBC > 500 μg/mL). Kinetic assays show that killing of S. sanguinis and S. mitis with sapienic acid is gradual and occurred within 24 h[1]. |
| References |
| Molecular Formula | C16H30O2 |
|---|---|
| Molecular Weight | 254.40800 |
| Exact Mass | 254.22500 |
| PSA | 37.30000 |
| LogP | 5.32830 |