CGS 27023A
Modify Date: 2025-11-19 16:53:48
CGS 27023A structure
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Common Name | CGS 27023A | ||
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| CAS Number | 169799-04-6 | Molecular Weight | 429.918 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H24ClN3O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CGS 27023ACGS 27023A (MMI 270) is a potent, orally active MMP inhibitor with Ki of 8-43 nM for MMP1/2/3/9. |
| Name | N-Hydroxy-N2-[(4-methoxyphenyl)sulfonyl]-N2-(3-pyridinylmethyl)-D-valinamide hydrochloride (1:1) |
|---|---|
| Synonym | More Synonyms |
| Description | CGS 27023A (MMI 270) is a potent, orally active MMP inhibitor with Ki of 8-43 nM for MMP1/2/3/9. |
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| In Vitro | CGS 27023A (MMI 270) is a potent, orally active MMP inhibitor with Ki of 8-43 nM for MMP1/2/3/9; shows growth-inhibitory effects in breast carcinoma, prostate, bladder, colon, lung adenocarcinoma, glioblastoma, and ovarian carcinoma cell line;.protects the cartilage proteoglycan matrix in a partial meniscectomy model of osteoarthritis in rabbits.Solid TumorsPhase 2 Discontinued |
| Molecular Formula | C18H24ClN3O5S |
|---|---|
| Molecular Weight | 429.918 |
| Exact Mass | 429.112518 |
| InChIKey | ZVYIZSNCEAHMCF-UNTBIKODSA-N |
| SMILES | COc1ccc(S(=O)(=O)N(Cc2cccnc2)C(C(=O)NO)C(C)C)cc1.Cl |
| N-Hydroxy-N2-[(4-methoxyphenyl)sulfonyl]-N2-(3-pyridinylmethyl)-D-valinamide hydrochloride (1:1) |
| Butanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](3-pyridinylmethyl)amino]-3-methyl-, (2R)-, hydrochloride (1:1) |