OSMI-1
Modify Date: 2025-08-29 11:48:12
OSMI-1 structure
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Common Name | OSMI-1 | ||
|---|---|---|---|---|
| CAS Number | 1681056-61-0 | Molecular Weight | 563.645 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C28H25N3O6S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of OSMI-1OSMI-1 is a cell-permeable, small molecule O-GlcNAc transferase (OGT) inhibitor with IC50 of 2.7 uM; inhibits protein O-GlcNAcylation in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans; also significantly decreases HSV replication. |
| Name | OSMI 1 |
|---|---|
| Synonym | More Synonyms |
| Description | OSMI-1 is a cell-permeable, small molecule O-GlcNAc transferase (OGT) inhibitor with IC50 of 2.7 uM; inhibits protein O-GlcNAcylation in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans; also significantly decreases HSV replication. |
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| References | References 1. Ortiz-Meoz RF, et al. ACS Chem Biol. 2015 Jun 19;10(6):1392-7. 2. Angelova M, et al. J Virol. 2015 Aug;89(16):8474-83. View Related Products by Target Other Targets |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C28H25N3O6S2 |
| Molecular Weight | 563.645 |
| Exact Mass | 563.118469 |
| LogP | 4.32 |
| Index of Refraction | 1.652 |
| OSMI-1 |
| (αR)-α-[[(1,2-Dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)-benzeneacetamide |
| OSMI 1 |
| Benzeneacetamide, α-[[(1,2-dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)-, (αR)- |
| (2R)-N-(2-Furylmethyl)-2-(2-methoxyphenyl)-2-{[(2-oxo-1,2-dihydro-6-quinolinyl)sulfonyl]amino}-N-(2-thienylmethyl)acetamide |