Terpendole I

Modify Date: 2024-10-05 10:20:17

Terpendole I Structure
Terpendole I structure
Common Name Terpendole I
CAS Number 167612-17-1 Molecular Weight 453.570
Density 1.4±0.1 g/cm3 Boiling Point 668.4±55.0 °C at 760 mmHg
Molecular Formula C27H35NO5 Melting Point N/A
MSDS N/A Flash Point 358.0±31.5 °C

 Use of Terpendole I


Terpendole I, a fungal indoloditerpene, is a ACAT (acyl-CoA: cholesterol acyltransferase) inhibitor (IC50=145 µM)[1].

 Names

Name Terpendole I
Synonym More Synonyms

 Terpendole I Biological Activity

Description Terpendole I, a fungal indoloditerpene, is a ACAT (acyl-CoA: cholesterol acyltransferase) inhibitor (IC50=145 µM)[1].
Related Catalog
Target

Microbial Metabolite

References

[1]. Tomoda H, et al. Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. III. Production, isolation and structure elucidation of new components. J Antibiot (Tokyo). 1995;48(8):793-804.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 668.4±55.0 °C at 760 mmHg
Molecular Formula C27H35NO5
Molecular Weight 453.570
Flash Point 358.0±31.5 °C
Exact Mass 453.251526
LogP 4.51
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.681

 Synonyms

2H,4bH-Oxireno[4',4a']-1-benzopyrano[5',6':6,7]indeno[1,2-b]indole-3,4b-diol, 3,3a,5,6,6a,7,12,12b,12c,13,14,14a-dodecahydro-2-(1-hydroxy-1-methylethyl)-12b,12c-dimethyl-, (2S,3R,3aR,4aS,4bS,6aS,12bS,12cR,14aS)-
Terpendole I
(2S,3R,3aR,4aS,4bS,6aS,12bS,12cR,14aS)-2-(2-Hydroxy-2-propanyl)-12b,12c-dimethyl-3,3a,5,6,6a,7,12,12b,12c,13,14,14a-dodecahydro-2H,4bH-oxireno[4',4a']chromeno[5',6':6,7]indeno[1,2-b]indole-3,4b-diol