Yp537

Modify Date: 2025-08-23 15:28:00

Yp537 structure	Common Name	Yp537
	CAS Number	166664-90-0	Molecular Weight	N/A
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₄H₁₀₄N₁₃O₂₂PS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Yp537

Yp537 is an estrogen receptor (ER) inhibitor that blocks dimerization of the human estrogen receptor[1].

Name	cys-asn-val-val-pro-leu-tyr(po3h2)-asp-&

Description	Yp537 is an estrogen receptor (ER) inhibitor that blocks dimerization of the human estrogen receptor[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Endocrinology
In Vitro	Yp537 (5-50 μM; 1 h) abolishes the formation of the hER-ERE complex. And dose not inhibit the formation of the STAT1-serum-induced element complex[1]. Yp537 binds to a SH2-like domain, and interferes with the SH2-like phosphopeptide coupling mechanism between hER monomers[1].
References	[1]. Arnold SF, et al. An antiestrogen: a phosphotyrosyl peptide that blocks dimerization of the human estrogen receptor. Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7475-9.

Molecular Formula	C₆₄H₁₀₄N₁₃O₂₂PS
Appearance of Characters	Solid \| White to off-white
Storage condition	−20°C

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: CYS-ASN-VAL-VAL-PRO-LEU-TYR(PO3H2)-ASP-&
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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