GpTx-1

Modify Date: 2024-01-16 22:04:31

GpTx-1 Structure
GpTx-1 structure
Common Name GpTx-1
CAS Number 1661050-12-9 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C176H271N53O45S7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GpTx-1


GpTx-1 is a potent, selective, 34-residue peptide antagonist of Nav1.7 sodium channel with IC50 of 10 nM, displays 20- and 1000- fold selectivity over NaV1.4 and NaV1.5.

 Names

Name GpTx-1

 GpTx-1 Biological Activity

Description GpTx-1 is a potent, selective, 34-residue peptide antagonist of Nav1.7 sodium channel with IC50 of 10 nM, displays 20- and 1000- fold selectivity over NaV1.4 and NaV1.5.
References References 1. Murray JK, et al. J Med Chem. 2015 Mar 12;58(5):2299-314. 2. Deuis JR, et al. Toxins (Basel). 2016 Mar 17;8(3). pii: E78. 3. Biswas K, et al. ACS Chem Biol. 2017 Sep 15;12(9):2427-2435. View Related Products by Target Sodium Channel

 Chemical & Physical Properties

Molecular Formula C176H271N53O45S7
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