1661050-12-9
1661050-12-9 structure
- Name: GpTx-1
- Chemical Name: GpTx-1
- CAS Number: 1661050-12-9
- Molecular Formula: C176H271N53O45S7
- Molecular Weight:
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
- Create Date: 2020-01-12 18:44:27
- Modify Date: 2024-01-16 22:04:31
-
GpTx-1 is a potent, selective, 34-residue peptide antagonist of Nav1.7 sodium channel with IC50 of 10 nM, displays 20- and 1000- fold selectivity over NaV1.4 and NaV1.5.
| Name | GpTx-1 |
|---|
| Description | GpTx-1 is a potent, selective, 34-residue peptide antagonist of Nav1.7 sodium channel with IC50 of 10 nM, displays 20- and 1000- fold selectivity over NaV1.4 and NaV1.5. |
|---|---|
| References | References 1. Murray JK, et al. J Med Chem. 2015 Mar 12;58(5):2299-314. 2. Deuis JR, et al. Toxins (Basel). 2016 Mar 17;8(3). pii: E78. 3. Biswas K, et al. ACS Chem Biol. 2017 Sep 15;12(9):2427-2435. View Related Products by Target Sodium Channel |
| Molecular Formula | C176H271N53O45S7 |
|---|