ZEN-3694

Modify Date: 2024-09-22 17:36:29

ZEN-3694 Structure
ZEN-3694 structure
Common Name ZEN-3694
CAS Number 1643947-30-1 Molecular Weight 333.39
Density N/A Boiling Point N/A
Molecular Formula C19H19N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ZEN-3694


ZEN-3694 is a bromo-structural domain extra-terminal inhibitor (BETi) with activity in androgen signaling inhibitor (ASI) resistance models and can be used in combination with enzalutamide to study metastatic desmoplasia-resistant prostate cancer.

 Names

Name ZEN-3694

 ZEN-3694 Biological Activity

Description ZEN-3694 is a bromo-structural domain extra-terminal inhibitor (BETi) with activity in androgen signaling inhibitor (ASI) resistance models and can be used in combination with enzalutamide to study metastatic desmoplasia-resistant prostate cancer.
References 1. Aggarwal RR, et al. A Phase Ib/IIa Study of the Pan-BET Inhibitor ZEN-3694 in Combination with Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer. Clin Cancer Res. 2020 Oct 15;26(20):5338-5347.

 Chemical & Physical Properties

Molecular Formula C19H19N5O
Molecular Weight 333.39