ZEN-3694
Names
[ CAS No. ]:
1643947-30-1
[ Name ]:
ZEN-3694
Biological Activity
[Description]:
ZEN-3694 is a bromo-structural domain extra-terminal inhibitor (BETi) with activity in androgen signaling inhibitor (ASI) resistance models and can be used in combination with enzalutamide to study metastatic desmoplasia-resistant prostate cancer.
[References]
1. Aggarwal RR, et al. A Phase Ib/IIa Study of the Pan-BET Inhibitor ZEN-3694 in Combination with Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer. Clin Cancer Res. 2020 Oct 15;26(20):5338-5347.
Chemical & Physical Properties
[ Molecular Formula ]:
C19H19N5O
[ Molecular Weight ]:
333.39