22-(tert-Butoxy)-22-oxodocosanoic acid

Modify Date: 2025-08-25 13:29:01

22-(tert-Butoxy)-22-oxodocosanoic acid Structure
22-(tert-Butoxy)-22-oxodocosanoic acid structure
Common Name 22-(tert-Butoxy)-22-oxodocosanoic acid
CAS Number 1642333-05-8 Molecular Weight 426.673
Density N/A Boiling Point N/A
Molecular Formula C26H50O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 22-(tert-Butoxy)-22-oxodocosanoic acid


22-(tert-Butoxy)-22-oxodocosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 22-(tert-Butoxy)-22-oxodocosanoic acid is also a alkyl chain-based PROTAC linker that can be used in t

 Names

Name 22-(tert-Butoxy)-22-oxodocosanoic acid
Synonym More Synonyms

 22-(tert-Butoxy)-22-oxodocosanoic acid Biological Activity

Description 22-(tert-Butoxy)-22-oxodocosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 22-(tert-Butoxy)-22-oxodocosanoic acid is also a alkyl chain-based PROTAC linker that can be used in t
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

[2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Molecular Formula C26H50O4
Molecular Weight 426.673
Exact Mass 426.370911

 Synonyms

22-[(2-Methyl-2-propanyl)oxy]-22-oxodocosanoic acid
Docosanedioic acid, mono(1,1-dimethylethyl) ester
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here



Get all suppliers and price by the below link:

22-(tert-Butoxy)-22-oxodocosanoic acid suppliers

22-(tert-Butoxy)-22-oxodocosanoic acid price

Related Compounds: More...
Docosanoic acid, 22-oxo-
1034470-39-7
22-methoxy-22-oxo-docosanoic acid
7511-30-0
11-tert-butoxy-3-dodecynoic acid
163631-28-5
14-(tert-Butoxy)-14-oxotetradecanoic acid
234082-00-9
11-(Tert-butoxy)-11-oxoundecanoic acid
1789702-17-5
20-(Tert-Butoxy)-20-Oxoicosanoic Acid
683239-16-9
Decanedioic acid, mono(1,1-dimethylethyl) ester
234081-96-0
3-tert-Butoxy-3-oxopropanoic acid
40052-13-9
3-tert-Butoxy-2-thiophenecarboxylic acid ethyl ester
5612-69-1
(2S)-2-({3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolan-2-yl}formamido)propanoic acid
2648913-62-4
3-({3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolan-2-yl}formamido)-2-methoxypropanoic acid
2172396-54-0
3-{[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(methylsulfanyl)butanamido]methyl}oxolane-2-carboxylic acid
2171425-34-4
3-{[(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(methylsulfanyl)butanamido]methyl}oxolane-2-carboxylic acid
2171417-12-0
rac-(2R,3R)-3-{[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanamido]methyl}oxolane-2-carboxylic acid
2228062-88-0
rac-2-cyclopropyl-2-{[(3R,5R)-5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolan-3-yl]formamido}acetic acid
2227930-90-5
(2S)-2-({5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolan-3-yl}formamido)-3-methylbutanoic acid
2648928-54-3
4-({5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolan-3-yl}formamido)-3-methylbutanoic acid
2172079-39-7
rac-(3R,5R)-5-({[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}methyl)oxolane-3-carboxylic acid
2228053-14-1
4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-methylhex-4-enamido]cyclopent-1-ene-1-carboxylic acid
2171709-25-2