tetrathiomolybdate structure
|
Common Name | tetrathiomolybdate | ||
|---|---|---|---|---|
| CAS Number | 16330-92-0 | Molecular Weight | 224.22000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | MoS4-- | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of tetrathiomolybdateTetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body. Tetrathiomolybdate has a protective effect on collagen-induced arthritis in mice. Tetrathiomolybdate also reduces blood sugar, but has no effect on mice with hereditary diabetes (db/db). Tetrathiomolybdate inhibit angiogenesis, also shows antiangiogenic effects in malignant pleural mesothelioma[1][2][3]. |
| Name | tetrathiomolybdate(2−) |
|---|
| Description | Tetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body. Tetrathiomolybdate has a protective effect on collagen-induced arthritis in mice. Tetrathiomolybdate also reduces blood sugar, but has no effect on mice with hereditary diabetes (db/db). Tetrathiomolybdate inhibit angiogenesis, also shows antiangiogenic effects in malignant pleural mesothelioma[1][2][3]. |
|---|---|
| Related Catalog | |
| In Vivo | Tetrathiomolybdate (0.2 mg/小鼠/天; 口服; 10 周)保护小鼠免受胶原诱导的关节炎,具有预防作用[1]。 Tetrathiomolybdate (0.03 mg/mL; 加在水中,8 周)通过减少肿胀和红斑抑制小鼠胶原诱导关节炎的进展[1]。 Animal Model: Collagen-induced arthritis model in mice[1] Dosage: 0.2 mg/mouse/day or 0.03 mg/mL, added in water Administration: Oral gavage, for 10 weeks; Collagen injected at weeks 2 Result: Showed significant preventive effect and protective effect in mice. |
| References |
| Molecular Formula | MoS4-- |
|---|---|
| Molecular Weight | 224.22000 |
| Exact Mass | 225.79400 |
| PSA | 64.18000 |
| LogP | 1.29160 |
| InChIKey | VVRHUOPINLMZBL-UHFFFAOYSA-L |
| SMILES | S=[Mo]=S.[SH-].[SH-] |