MOG (35-55), human

Modify Date: 2024-01-09 17:01:43

MOG (35-55), human Structure
MOG (35-55), human structure
Common Name MOG (35-55), human
CAS Number 163158-19-8 Molecular Weight 2591.99000
Density N/A Boiling Point N/A
Molecular Formula C120H179N35O28S Melting Point N/A
MSDS USA Flash Point N/A

 Use of MOG (35-55), human


MOG (35-55), human is a component of CNS myelin. MOG (35-55), human is different from mMOG (35-55) by a proline for serine substitution at position 42. MOG (35-55), human is also immunogenic, but not encephalitogenic, and is only partially cross-reactive with mMOG35–55. MOG (35-55), human induces minimal clinical signs of EAE relative to the rodent peptide[1].

 Names

Name h-met-glu-val-gly-trp-tyr-arg-pro-pro-phe-ser-arg-val-val-his-leu-tyr-arg-asn-gly-lys-oh
Synonym More Synonyms

 MOG (35-55), human Biological Activity

Description MOG (35-55), human is a component of CNS myelin. MOG (35-55), human is different from mMOG (35-55) by a proline for serine substitution at position 42. MOG (35-55), human is also immunogenic, but not encephalitogenic, and is only partially cross-reactive with mMOG35–55. MOG (35-55), human induces minimal clinical signs of EAE relative to the rodent peptide[1].
Related Catalog
References

[1]. Cathleen Rich, et al. Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice. Eur J Immunol. 2004 May;34(5):1251-61.

[2]. Alfred R Oliver, et al.Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 mice. J Immunol. 2003 Jul 1;171(1):462-8.

 Chemical & Physical Properties

Molecular Formula C120H179N35O28S
Molecular Weight 2591.99000
Exact Mass 2590.34000
PSA 1050.31000
LogP 6.20280

 Synonyms

h2n-mevgwyrppfsrvvhlyrngk-oh
myelin oligodendrocyte glycoprotein precursor