DMX-129

Modify Date: 2023-04-02 11:40:05

Use of DMX-129

DMX-129 is an ΙΚΚε and TBK-1 inhibitor with IC50 values of <30 nM for both TBK1 and IKKε[1].

Name	DMX-129

Description	DMX-129 is an ΙΚΚε and TBK-1 inhibitor with IC50 values of <30 nM for both TBK1 and IKKε[1].
Related Catalog	Signaling Pathways >> NF-κB >> IKK Research Areas >> Cancer
Target	IC50: <30 nM (TBK-1), <30 nM (ΙΚΚε)[1]
References	[1]. Gary Karl Newton, et al. Pyrimidine compounds useful in the treatment of diseases mediated by ikke and/or tbk1 mechanisms. Patent WO2014128486A1.

Molecular Formula	C₁₉H₁₇FN₈
Molecular Weight	376.39