DMX-129

Names

[ CAS No. ]:
1623123-95-4

[ Name ]:
DMX-129

Biological Activity

[Description]:

DMX-129 is an ΙΚΚε and TBK-1 inhibitor with IC50 values of <30 nM for both TBK1 and IKKε[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> IKK
Research Areas >> Cancer

[Target]

IC50: <30 nM (TBK-1), <30 nM (ΙΚΚε)[1]


[References]

[1]. Gary Karl Newton, et al. Pyrimidine compounds useful in the treatment of diseases mediated by ikke and/or tbk1 mechanisms. Patent WO2014128486A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H17FN8

[ Molecular Weight ]:
376.39

Related Compounds