12-Oxocalanolide A
Modify Date: 2025-09-09 17:24:14
12-Oxocalanolide A structure
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Common Name | 12-Oxocalanolide A | ||
|---|---|---|---|---|
| CAS Number | 161753-49-7 | Molecular Weight | 368.42 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 546.7±50.0 °C at 760 mmHg | |
| Molecular Formula | C22H24O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 298.4±18.1 °C | |
Use of 12-Oxocalanolide A12-Oxocalanolide A (compound 6) is a potent inhibitor of reverse transcriptase from human immunodeficiency virus type 1 (HIV-1) with an IC50 and EC50 of 2.8 and 12 μM, respectively. 12-Oxocalanolide A is the analogue of Calanolide[1]. |
| Name | 12-Oxocalanolide A |
|---|---|
| Synonym | More Synonyms |
| Description | 12-Oxocalanolide A (compound 6) is a potent inhibitor of reverse transcriptase from human immunodeficiency virus type 1 (HIV-1) with an IC50 and EC50 of 2.8 and 12 μM, respectively. 12-Oxocalanolide A is the analogue of Calanolide[1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 546.7±50.0 °C at 760 mmHg |
| Molecular Formula | C22H24O5 |
| Molecular Weight | 368.42 |
| Flash Point | 298.4±18.1 °C |
| Exact Mass | 368.162384 |
| PSA | 65.74000 |
| LogP | 5.90 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.550 |
| InChIKey | HQVBDUZROQMWRN-VXGBXAGGSA-N |
| SMILES | CCCc1cc(=O)oc2c3c(c4c(c12)OC(C)(C)C=C4)OC(C)C(C)C3=O |
| Hazard Codes | Xi |
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| (10R,11R)-6,6,10,11-Tetramethyl-4-propyl-10,11-dihydro-2H,6H,12H-dipyrano[2,3-f:2',3'-h]chromene-2,12-dione |
| 2H,6H,12H-Benzo[1,2-b:3,4-b':5,6-b'']tripyran-2,12-dione, 10,11-dihydro-6,6,10,11-tetramethyl-4-propyl-, (10R,11R)-rel- |
| 2H,6H,12H-Benzo[1,2-b:3,4-b':5,6-b'']tripyran-2,12-dione, 10,11-dihydro-6,6,10,11-tetramethyl-4-propyl-, (10R,11R)- |