KBP-7018 hydrochloride
Modify Date: 2025-09-06 12:10:53
KBP-7018 hydrochloride structure
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Common Name | KBP-7018 hydrochloride | ||
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| CAS Number | 1613437-67-4 | Molecular Weight | 575.06 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C31H31ClN4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of KBP-7018 hydrochlorideA novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively; also potently inhibits FLT3, VEGFR2, Fyn, PDGFRα and VEGFR2; shows promising outcomes for the treatments of idiopathic pulmonary fibrosis (IPF). |
| Name | KBP-7018 hydrochloride |
|---|
| Description | A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively; also potently inhibits FLT3, VEGFR2, Fyn, PDGFRα and VEGFR2; shows promising outcomes for the treatments of idiopathic pulmonary fibrosis (IPF). |
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| References | References 1. Huang Z, et al. ACS Med Chem Lett. 2017 Sep 30;8(11):1142-1147. 2. Huang Z, et al. Drug Des Devel Ther. 2015 Aug 5;9:4319-28. View Related Products by Target c-Kit |
| Molecular Formula | C31H31ClN4O5 |
|---|---|
| Molecular Weight | 575.06 |
| InChIKey | UMGLHWOHRLPZLT-UHFFFAOYSA-N |
| SMILES | COC(=O)c1ccc2c(C(=Nc3ccc4c(c3)CCN4C(=O)CN3CCOCC3)c3ccccc3)c(O)[nH]c2c1.Cl |