VNRX-5133
Modify Date: 2024-01-06 20:37:53
VNRX-5133 structure
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Common Name | VNRX-5133 | ||
|---|---|---|---|---|
| CAS Number | 1613268-23-7 | Molecular Weight | 389.25 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H28BN3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VNRX-5133VNRX-5133 is a cyclic boronate β-lactamase inhibitor. VNRX-5133 has direct inhibitory activity against serine-active site β-lactamases (Ser-BL) and metallo-β-lactamases (MBL). VNRX-5133 is highly active against multidrug-resistant (MDR)-K. pneumonia and P. aeruginosa clinical isolates[1]. |
| Name | VNRX-5133 |
|---|
| Description | VNRX-5133 is a cyclic boronate β-lactamase inhibitor. VNRX-5133 has direct inhibitory activity against serine-active site β-lactamases (Ser-BL) and metallo-β-lactamases (MBL). VNRX-5133 is highly active against multidrug-resistant (MDR)-K. pneumonia and P. aeruginosa clinical isolates[1]. |
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| Related Catalog | |
| Target |
β-lactamase[1] |
| In Vitro | VNRX-5133 is a potent β-lactamase inhibitor (BLI) possessing a unique broad spectrum of activity, including Class A, C, and D Ser-BLs. VNRX-5133 enhances the activity of Cefepime against resistant Enterobacteriaceae and P. aeruginosa isolates in a neutropenic mouse-thigh infection model[1]. |
| References |
| Molecular Formula | C19H28BN3O5 |
|---|---|
| Molecular Weight | 389.25 |