2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside

Modify Date: 2025-11-27 07:05:20

2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside Structure
2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside structure
Common Name 2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside
CAS Number 1612192-01-4 Molecular Weight 370.79
Density N/A Boiling Point N/A
Molecular Formula C14H12ClFN4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside


2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside

  Biological Activity

Description 2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C14H12ClFN4O3S
Molecular Weight 370.79
InChIKey HHDRPJYWNFGOEM-KMEHANEDSA-N
SMILES OCC1OC(n2cnc3c(-c4ccsc4)nc(Cl)nc32)C(O)C1F
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