Amt-87
Modify Date: 2024-04-11 23:10:10
Amt-87 structure
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Common Name | Amt-87 | ||
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| CAS Number | 1609019-52-4 | Molecular Weight | 492.612 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H36O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Amt-87Amt-87 is a HIV latency-reversal agent that reactivates latent HIV at the transcriptional level, promotes phosphorylation of CDK9 T-loop at Thr186; induces P-TEFb dissociation from 7SK snRNP and promotes Tat-SEC formation on HIV-1 LTR, dissociates P-TEFb from 7SK snRNP and promotes Tat-SEC formation at the HIV-1 promoter; synergizes with prostratin and JQ1 to reverse HIV latency and reactivate viral transcription. |
| Name | Amt-87 |
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| Description | Amt-87 is a HIV latency-reversal agent that reactivates latent HIV at the transcriptional level, promotes phosphorylation of CDK9 T-loop at Thr186; induces P-TEFb dissociation from 7SK snRNP and promotes Tat-SEC formation on HIV-1 LTR, dissociates P-TEFb from 7SK snRNP and promotes Tat-SEC formation at the HIV-1 promoter; synergizes with prostratin and JQ1 to reverse HIV latency and reactivate viral transcription. |
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| References | References 1. Wu J, et al. Sci Rep. 2017 Sep 6;7(1):10657. View Related Products by Target Cyclin-dependent Kinase (CDK) |
| Molecular Formula | C30H36O6 |
|---|---|
| Molecular Weight | 492.612 |