<Suppliers Price>

Amt-87

Names

[ CAS No. ]:
1609019-52-4

[ Name ]:
Amt-87

Biological Activity

[Description]:

Amt-87 is a HIV latency-reversal agent that reactivates latent HIV at the transcriptional level, promotes phosphorylation of CDK9 T-loop at Thr186; induces P-TEFb dissociation from 7SK snRNP and promotes Tat-SEC formation on HIV-1 LTR, dissociates P-TEFb from 7SK snRNP and promotes Tat-SEC formation at the HIV-1 promoter; synergizes with prostratin and JQ1 to reverse HIV latency and reactivate viral transcription.

[References]

References 1. Wu J, et al. Sci Rep. 2017 Sep 6;7(1):10657. View Related Products by Target Cyclin-dependent Kinase (CDK)

Chemical & Physical Properties

[ Molecular Formula ]:
C30H36O6

[ Molecular Weight ]:
492.612


Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.