L -Kynurenine sulfate salt
L -Kynurenine sulfate salt structure
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Common Name | L -Kynurenine sulfate salt | ||
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| CAS Number | 16055-80-4 | Molecular Weight | 306.29200 | |
| Density | N/A | Boiling Point | 466.6ºC at 760 mmHg | |
| Molecular Formula | C10H14N2O7S | Melting Point | 196 °C | |
| MSDS | Chinese USA | Flash Point | 236ºC | |
Use of L -Kynurenine sulfate saltL-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype[1]. |
| Name | (S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid compound with sulfuric acid (1:1) |
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| Synonym | More Synonyms |
| Description | L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype[1]. |
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| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
| Boiling Point | 466.6ºC at 760 mmHg |
|---|---|
| Melting Point | 196 °C |
| Molecular Formula | C10H14N2O7S |
| Molecular Weight | 306.29200 |
| Flash Point | 236ºC |
| Exact Mass | 306.05200 |
| PSA | 189.39000 |
| LogP | 1.96300 |
| Vapour Pressure | 1.66E-09mmHg at 25°C |
| Storage condition | -20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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~63%
L -Kynurenine s... CAS#:16055-80-4 |
| Literature: Kleijn, Laurens H.J.; Mueskens, Frederike M.; Oppedijk, Sabine F.; De Bruin, Gerjan; Martin, Nathaniel I. Tetrahedron Letters, 2012 , vol. 53, # 47 p. 6430 - 6432 |
| Precursor 1 | |
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| DownStream 0 | |
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Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts.
J. Inflamm. (Lond.) 8 , 25, (2011) The kynurenine pathway (KP) is the main route of tryptophan degradation in the human body and generates several neuroactive and immunomodulatory metabolites. Altered levels of KP-metabolites have been... |
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The L-kynurenine signalling pathway in trigeminal pain processing: a potential therapeutic target in migraine?
Cephalalgia 31 , 1029-1038, (2011) In recent years the kynurenine family of compounds, metabolites of tryptophan, has become an area of intensive research because of its neuroactive properties. Two metabolites of this family have becom... |
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Inhibition of indoleamine 2,3-dioxygenase activity by levo-1-methyl tryptophan blocks gamma interferon-induced Chlamydia trachomatis persistence in human epithelial cells.
Infect. Immun. 79 , 4425-4437, (2011) Gamma interferon (IFN-γ) induces expression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO1) in human epithelial cells, the permissive cells for the obligate intracellular bact... |
| L-kynurenin,sulfate |
| L-KYNURENINESULPHATE |
| L-Kynurenin,Sulfat |
| L-Kynurenine sulfate salt crystalline |
| Kyn sulfate |
| L-Kynurenine sulfate salt |