Tilfrinib
Modify Date: 2025-08-24 17:28:34
Tilfrinib structure
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Common Name | Tilfrinib | ||
|---|---|---|---|---|
| CAS Number | 1600515-49-8 | Molecular Weight | 275.305 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 560.6±35.0 °C at 760 mmHg | |
| Molecular Formula | C17H13N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 292.8±25.9 °C | |
Use of TilfrinibTilfrinib (compound 4f) is a potent and selective inhibitor of breast tumor kinase (Brk) with an IC50 of 3.15 nM, which displays anti-proliferative activity and acts as a promising antitumor agent[1]. |
| Name | 3-(9H-Pyrido[2,3-b]indol-4-ylamino)phenol |
|---|---|
| Synonym | More Synonyms |
| Description | Tilfrinib (compound 4f) is a potent and selective inhibitor of breast tumor kinase (Brk) with an IC50 of 3.15 nM, which displays anti-proliferative activity and acts as a promising antitumor agent[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 3.15 nM (Brk)[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 560.6±35.0 °C at 760 mmHg |
| Molecular Formula | C17H13N3O |
| Molecular Weight | 275.305 |
| Flash Point | 292.8±25.9 °C |
| Exact Mass | 275.105865 |
| LogP | 4.69 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.839 |
| InChIKey | RXPZOSHFGJWSLQ-UHFFFAOYSA-N |
| SMILES | Oc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1 |
| 3-(9H-Pyrido[2,3-b]indol-4-ylamino)phenol |
| Phenol, 3-(9H-pyrido[2,3-b]indol-4-ylamino)- |
| MFCD30011871 |