1600515-49-8
1600515-49-8 structure
- Name: Tilfrinib
- Chemical Name: 3-(9H-Pyrido[2,3-b]indol-4-ylamino)phenol
- CAS Number: 1600515-49-8
- Molecular Formula: C17H13N3O
- Molecular Weight: 275.305
- Catalog: Research Areas Cancer
- Create Date: 2018-07-07 03:39:54
- Modify Date: 2025-08-24 17:28:34
-
Tilfrinib (compound 4f) is a potent and selective inhibitor of breast tumor kinase (Brk) with an IC50 of 3.15 nM, which displays anti-proliferative activity and acts as a promising antitumor agent[1].
| Name | 3-(9H-Pyrido[2,3-b]indol-4-ylamino)phenol |
|---|---|
| Synonyms |
3-(9H-Pyrido[2,3-b]indol-4-ylamino)phenol
Phenol, 3-(9H-pyrido[2,3-b]indol-4-ylamino)- MFCD30011871 |
| Description | Tilfrinib (compound 4f) is a potent and selective inhibitor of breast tumor kinase (Brk) with an IC50 of 3.15 nM, which displays anti-proliferative activity and acts as a promising antitumor agent[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 3.15 nM (Brk)[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 560.6±35.0 °C at 760 mmHg |
| Molecular Formula | C17H13N3O |
| Molecular Weight | 275.305 |
| Flash Point | 292.8±25.9 °C |
| Exact Mass | 275.105865 |
| LogP | 4.69 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.839 |