UU-T03
Modify Date: 2025-09-24 12:06:47
UU-T03 structure
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Common Name | UU-T03 | ||
|---|---|---|---|---|
| CAS Number | 1586007-00-2 | Molecular Weight | 721.204 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C37H41ClN4O9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of UU-T03UU-T03 is the ethyl ester derivative of UU-T02, which is a potent, selective inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM; exhibits growth inhibition of SW480 cells with IC50 of 10.77 uM; downregulates the transcription of AXIN2, LGR5, cyclin D1, and c-Myc in dose-dependent manners in SW480 cells. |
| Name | UU-T03 |
|---|
| Description | UU-T03 is the ethyl ester derivative of UU-T02, which is a potent, selective inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM; exhibits growth inhibition of SW480 cells with IC50 of 10.77 uM; downregulates the transcription of AXIN2, LGR5, cyclin D1, and c-Myc in dose-dependent manners in SW480 cells. |
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| References | References 1. Huang Z, et al. ACS Chem Biol. 2014 Jan 17;9(1):193-201. View Related Products by Target Beta-catenin |
| Molecular Formula | C37H41ClN4O9 |
|---|---|
| Molecular Weight | 721.204 |
| InChIKey | OEJMKUIYROSICC-CHQNGUEUSA-N |
| SMILES | CCOC(=O)CCC(NC(=O)C(CC(=O)OCC)NC(=O)C(Cc1ccc2ccccc2c1)NC(=O)Cc1cc2cc(Cl)ccc2[nH]1)C(=O)OC |