UU-T03
Names
[ CAS No. ]:
1586007-00-2
[ Name ]:
UU-T03
Biological Activity
[Description]:
UU-T03 is the ethyl ester derivative of UU-T02, which is a potent, selective inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM; exhibits growth inhibition of SW480 cells with IC50 of 10.77 uM; downregulates the transcription of AXIN2, LGR5, cyclin D1, and c-Myc in dose-dependent manners in SW480 cells.
[References]
References 1. Huang Z, et al. ACS Chem Biol. 2014 Jan 17;9(1):193-201. View Related Products by Target Beta-catenin
Chemical & Physical Properties
[ Molecular Formula ]:
C37H41ClN4O9
[ Molecular Weight ]:
721.204
Related Compounds
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