6,8-Difluoro-1-(formylmethylamino)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ethyl ester

Modify Date: 2024-02-02 19:01:52

6,8-Difluoro-1-(formylmethylamino)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ethyl ester Structure
6,8-Difluoro-1-(formylmethylamino)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ethyl ester structure
Common Name 6,8-Difluoro-1-(formylmethylamino)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ethyl ester
CAS Number 158585-86-5 Molecular Weight 408.39900
Density 1.41 Boiling Point 543.7ºC at 760 mmHg
Molecular Formula C19H22F2N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name ethyl 6,8-difluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1-(2-oxoethylamino)quinoline-3-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.41
Boiling Point 543.7ºC at 760 mmHg
Molecular Formula C19H22F2N4O4
Molecular Weight 408.39900
Exact Mass 408.16100
PSA 83.88000
LogP 1.02650
Index of Refraction 1.612

 Synthetic Route

~%

6,8-Difluoro-1-(formylmethylamino)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ethyl ester Structure

6,8-Difluoro-1-...

CAS#:158585-86-5

Literature: US5892040 A1, ;

~58%

6,8-Difluoro-1-(formylmethylamino)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ethyl ester Structure

6,8-Difluoro-1-...

CAS#:158585-86-5

Literature: KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO; ZUPET, Rok; ISKRA, Jernej; RUZIC, Milos; PECAVAR, Anica; KOLENC, Ivanka; PUCELJ, Joze; PLAPER, Igor Patent: WO2011/61292 A1, 2011 ; Location in patent: Page/Page column 43-44 ;

 Synonyms

3-Quinolinecarboxylicacid,6,8-difluoro-1-(formylmethylamino)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-,ethyl ester
Ethyl6,8-difluoro-1,4-dihydro-1-(N-methylformamido)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylate
6,8-difluoro-1-(N-methylformamido)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-quinoline-3-carboxylic acid ethyl ester
I06-2622
6,8-DIFLUORO-1-(FORMYLMETHYLAMINO)-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
ethyl 6,8-difluoro-1-(N-methylformamido)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate